TY - JOUR

T1 - Structure and function of masticatory muscles in a case of muscular dystrophy

AU - Bakke, M

AU - Kirkeby, S

AU - Jensen, B L

AU - Hansen, H J

AU - Kreiborg, S

AU - Hjørting-Hansen, E

AU - Michler, L

AU - Møller, E

N1 - Keywords: Adult; Bite Force; Electromyography; Humans; Male; Mandible; Masticatory Muscles; Movement; Muscle Contraction; Muscular Dystrophies; Myosins; Neck Muscles; Succinate Dehydrogenase

PY - 1990

Y1 - 1990

N2 - Histologic examination of muscle biopsies and functional examination comprising electromyography and force measurements in a 19-yr-old boy with muscular dystrophy showed different wasting patterns of mandibular elevator and depressor muscles. Pronounced histopathologic changes were present in the masseter muscle, whereas pathologic findings in the anterior digastric muscle were limited to increased number of cells in slightly enlarged interfiber connective tissue. The masticatory pattern was distorted, and strength of mandibular elevator muscles was less than one third of the norm, whereas depressor strength corresponded more to reference values. This difference of muscular wasting might be caused by protective enzymes in the digastric muscle and/or functionally induced damage of the masseter. As affection from muscular dystrophy may vary greatly between the masticatory muscles, structural and functional examination should be used routinely to clarify prognosis before initiation of treatment procedures.

AB - Histologic examination of muscle biopsies and functional examination comprising electromyography and force measurements in a 19-yr-old boy with muscular dystrophy showed different wasting patterns of mandibular elevator and depressor muscles. Pronounced histopathologic changes were present in the masseter muscle, whereas pathologic findings in the anterior digastric muscle were limited to increased number of cells in slightly enlarged interfiber connective tissue. The masticatory pattern was distorted, and strength of mandibular elevator muscles was less than one third of the norm, whereas depressor strength corresponded more to reference values. This difference of muscular wasting might be caused by protective enzymes in the digastric muscle and/or functionally induced damage of the masseter. As affection from muscular dystrophy may vary greatly between the masticatory muscles, structural and functional examination should be used routinely to clarify prognosis before initiation of treatment procedures.

M3 - Journal article

C2 - 2146387

VL - 19

SP - 335

EP - 340

JO - Journal of Oral Pathology and Medicine

JF - Journal of Oral Pathology and Medicine

SN - 0904-2512

IS - 7

ER -